利用vb.net操作excel2010时，出现异常错误，如何修改？

Imports Microsoft.Office.Interop
Imports Microsoft.Office.Core

Public Class Form1
    Private Sub Button2_Click(ByVal sender As System.Object, ByVal e As System.EventArgs) Handles Button2.Click

            Dim myapp As Excel.Application
            Dim mybook As Excel.Workbook
            Dim mysheet As Excel.Worksheet
            Dim filename As String

            filename = "E:\vb2010\4\13.xlsx"
            myapp = CreateObject("Excel.application")
            myapp.Visible = False
            mybook = myapp.Workbooks.Open(filename)
            mysheet = mybook.Worksheets("sheet1")

            myapp.Quit()
            mysheet = Nothing
            mybook = Nothing
            myapp = Nothing
   
    End Sub
End Class
运行时出现错误：
   检查异常的ErrorCode 属性以确定COM对象返回的HRESULT.

[此贴子已经被作者于2021-11-5 09:01编辑过]